About Our EpiCTAVax Technology

From Mesenchymal Stromal Cells (MSCs) to a Multi-Antigen Cellular Vaccine

Our Approach

High-resolution cellular imaging illustrating advanced cancer vaccine research and immuno-oncology innovation

msc isolation

We leverage MSCs as a cellular vaccine platform due to their unique plasticity, ease of isolation and expansion, as well as their ability to present multiple antigens simultaneously while maintaining favorable safety profiles. Our mandate is to leverage our robust platform to create prophylactic vaccines and immuno-therapies to fight multiple forms of cancer.

Reprogramming

We treat MSCs with specific drugs to reactivate silenced genes known to be expressed by cancer cells.

Cellular Vaccine

Reprogrammed MSCs can express multiple cancer antigens simultaneously, creating a polyvalent vaccine capable of triggering broad and more efficient anti-tumor immune responses compared to standard immunotherapies.

TECHNOLOGY

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MSC
ISOLATION

Access to a defined Master Cell Bank (MSC).

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Reprogramming
Treatment

Treat MSCs with a proprietary recipe to activate CTA gene transcription.

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CTA
Expression

Robust induction of multiple Cancer-Testis Antigen (CTA) families.

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Cellular Vaccine

Reprogrammed MSCs serve as living vaccines, presenting multiple CTAs to stimulate a diversified anti-tumor immune and therapeutic responses to a defined Master Cell Bank.

pipeline

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